Heart, Lung and Circulation
Volume 15, Issue 1 , Pages 3-11, February 2006

ICD Therapy: What Have We Learned From the Clinical Trials?

Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Mellat Park, Vali-e-Asr Avenue, Tehran 1996911151, Iran

Development of implantable cardioverter defibrillators (ICD) has been a dramatic advancement in the management of patients with life-threatening ventricular arrhythmias. We hereby reviewed the landmark clinical trials on ICD with special emphasis on late-breaking clinical trials and assessed their impact on every-day decision making and patient selection for ICD implantation.

Keywords: Implantable cardioverter hdefibrillator, Primary prevention, Ventricular arrhythmia, Clinical trial, Cardiac resynchronization, Sudden cardiac death

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PII: S1443-9506(05)00151-4

doi:10.1016/j.hlc.2005.08.002

Heart, Lung and Circulation
Volume 15, Issue 1 , Pages 3-11, February 2006