Heart, Lung and Circulation
Volume 17, Issue 5 , Pages 357-363, October 2008

Management of the Ascending Aorta in Patients with Bicuspid Aortic Valve Disease

  • Michael P. Vallely, PhD, FRACS

      Affiliations

    • The Baird Institute, Sydney, Australia
    • Corresponding Author InformationCorresponding author. Tel.: +61295502350.
    • ,
  • Christopher Semsarian, PhD, FRACP

      Affiliations

    • Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Sydney, Australia
    • Department of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia
    • Central Clinical School, Faculty of Medicine, University of Sydney, Sydney, Australia
    • ,
  • Paul G. Bannon, PhD, FRACS

      Affiliations

    • The Baird Institute, Sydney, Australia
    • Central Clinical School, Faculty of Medicine, University of Sydney, Sydney, Australia
    • Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia

Received 14 September 2007; received in revised form 5 December 2007; accepted 23 January 2008.

Bicuspid aortic valve (BAV) disease is the most common form of congenital heart disease, affecting 1–2% of the population. Only 20% of patients will maintain normal valve function throughout their life and more than 30% of patients will develop serious morbidity. It is a highly heritable condition, with transmission likely to be autosomal dominant. Patients with BAV have a 10-fold risk of aortic dissection when compared to the normal population. Management of BAV associated aortopathy represents a significant clinical challenge.

Keywords: Bicuspid aortic valve, Aortic dissection

 

PII: S1443-9506(08)00040-1

doi:10.1016/j.hlc.2008.01.007

Heart, Lung and Circulation
Volume 17, Issue 5 , Pages 357-363, October 2008

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