Heart, Lung and Circulation
Volume 19, Issue 4 , Pages 251-252 , April 2010

Different Patterns of Circulatory Shunting in Zebrafish Caldesmon Morphants: A Digital Motion Analysis

  • Ping-Pin Zheng

      Affiliations

    • Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Lies-Anne Severijnen

      Affiliations

    • Department of CBG – Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Rob Willemsen

      Affiliations

    • Department of CBG – Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
    • These authors contributed equally to this work.
    • ,
  • Johan M. Kros, MD, PhD

      Affiliations

    • Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands
    • These authors contributed equally to this work.
    • Corresponding Author InformationCorresponding author at: Department of Pathology, Erasmus Medical Center, Office JNI Room 230-c, Dr. Molewaterplein 50, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. Tel.: +31 10 7043905; fax: +31 10 7043905.

Received 2 August 2009 ,Accepted 7 August 2009.

References 

  1. Zheng PP, Sieuwerts AM, Luider TM, van der Weiden M, Sillevis-Smitt PA, Kros JM. Differential expression of splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization versus normal brain microvasculature. Am J Pathol. 2004;164:2217–2228
  2. Zheng PP, Weiden M, Sillevis Smitt PA, Luider TM, Kros JM. Hela/-CaD undergoes a DNA replication-associated switch in localization from the cytoplasm to the nuclei of endothelial cells/endothelial progenitor cells in human tumor vasculature. Cancer Biol Ther. 2007;6:886–890
  3. Zheng PP, van der Weiden M, Kros JM. Hela l-CaD is implicated in the migration of endothelial cells/endothelial progenitor cells in human neoplasms. Cell Adh Migr. 2007;1:84–91
  4. Zheng PP, Severijnen LA, van der Weiden M, Willemsen R, Kros JM. A crucial role of caldesmon in vascular development in vivo. Cardiovasc Res. 2009;81:362–369

PII: S1443-9506(09)01053-1

doi: 10.1016/j.hlc.2009.08.007

Heart, Lung and Circulation
Volume 19, Issue 4 , Pages 251-252 , April 2010

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