Heart, Lung and Circulation RSS feed: Articles in Press. Heart, Lung and Circulation publishes articles integrating clinical and research activities in the fields of basic cardiovascular science, clinical cardiology and cardiac surgery, with a focus on emerging issues in cardiovascular disease. The journal promotes multidisciplinary dialogue between cardiologists, cardiothoracic surgeons, cardio-pulmonary physicians and cardiovascular scientists. The journal accepts original articles, current reviews, brief communications, and letters to the Editor, concerned with clinical practice and research in all fields of cardiovascular disease. The journal particularly invites submissions concerned with the issues of cardiovascular ageing, indigenous cardiovascular health, devices, tissue repair and replacement. To purchase books on Cardiology or to browse our comprehensive range of Medical titles, please visit us at shop.elsevier.com.au. Shop.elsevier.com.au/Cardiology Awarded its first Impact factor for 2010! http://www.heartlungcirc.org//inpress?rss=yesElsevier Inc.en © 2011 Published by Elsevier Inc. Heart, Lung and Circulation1443-95062011-10-17 © 2011 Published by Elsevier Inc. healthpermissions@elsevier.comhttp://www.heartlungcirc.org/article/PIIS1443950611010377/abstract?rss=yesWe present the case of a 48 year-old male with a history of cystic fibrosis who presented with massive haemoptysis and was later found to have Takotsubo cardiomyopathy. He subsequently developed a left ventricular (LV) thrombus which was successfully removed via a left apical ventriculotomy. Surgical management of LV thrombus related to Takotsubo cardiomyopathy is warranted in a selected population of patients and a left apical ventriculotomy provides good access with minimal complications in the post operative setting.A Rare Cause of Takotsubo Cardiomyopathy Related Left Ventricular Apical Thrombus Requiring Surgery - Corrected ProofMichael J. Seitz, Martin K. McLeod, Michael D. O’Keefe, Peng W. Seah10.1016/j.hlc.2011.07.004Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS144395061101050X/abstract?rss=yesLeft-ventricular non-compaction may be isolated or associated with other cardiac or noncardiac anomalies. Left-ventricular non-compaction associated with left ventricular diverticulum is very rare. We describe a 30 year-old pregnant woman with a long standing diagnosis of biventricular non-compaction in whom a hidden left ventricular apical diverticulum was detected on transthoracic echocardiography. Both these conditions increase the risk of thromboembolism. Additionally, she was also diagnosed to have endocervical adenocarcinoma. This case suggests that a comprehensive echocardiographic examination is mandatory in cases of suspected isolated left-ventricular non-compaction to detect any other associated cardiac or noncardiac anomalies.Left-Ventricular Non-Compaction with Congenital Left Ventricular Diverticulum - Corrected ProofPrashanth Panduranga, Eapen Thomas, Mohammed Al-Mukhaini10.1016/j.hlc.2011.07.012Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010547/abstract?rss=yesBeing considered as an uncommon congenital anomaly, pulmonary bronchogenic cyst requires surgical treatment due to its rarity and mortality especially in complicated forms. In the present paper, we are presenting a case report of a giant pulmonary bronchogenic cyst (18cm×15cm×10cm) misdiagnosed with loculated pleural effusion. Because of unsuccessful treatment of tube thoracostomy, the patient was scheduled for left thoracotomy. Later giant pulmonary cyst was removed completely without any complications. Histopathology studies revealed a giant bronchogenic cyst with abscess formation.A pitfall in the diagnosis of giant bronchogenic cyst presented as loculated pleural effusion - Corrected ProofSeyed Ziaedin Rasihashemi, Mohsen Sokouti, Farshid Bozorgi10.1016/j.hlc.2011.07.016Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010584/abstract?rss=yesLaparoscopic surgical procedures involving the gastro-oesophageal region are commonly performed for the management of morbid obesity and refractory gastro-oesophageal reflux disease (GORD). In general, laparoscopic procedures are associated with lower morbidity and mortality in comparison with open techniques. This report highlights cases of potentially life threatening, late onset pericardial tamponade, occurring in the absence of infection or trauma, complicating laparoscopic gastro-oesophageal surgery. Possible mechanisms, clinical manifestations, diagnostic investigations and management of pericardial tamponade are reviewed.Pericardial Tamponade: A Life Threatening Complication of Laparoscopic Gastro-oesophageal Surgery - Corrected ProofHariharan Sugumar, Leighton G. Kearney, Piyush M. Srivastava10.1016/j.hlc.2011.08.002Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010602/abstract?rss=yesHerein we describe a case of marantic endocarditis (non-bacterial thrombotic endocarditis) that presented with coronary, cerebral and peripheral emboli, fevers and malaise, and negative blood cultures. The ‘kissing lesions’ on all three leaflets of the aortic valve were bulky and friable. After aortic valve surgery, an acute abdomen prompted laparoscopy which demonstrated disseminated adenocarcinoma. We discuss the clinical presentation of this rare condition and the importance of considering marantic endocarditis secondary to malignancy as a differential diagnosis for culture negative endocarditis.Stroke, Aortic Vegetations and Disseminated Adenocarcinoma – A Case of Marantic Endocarditis - Corrected ProofGregory M. Scalia, Anmol K. Tandon, Jessica A. Robertson10.1016/j.hlc.2011.08.003Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010626/abstract?rss=yesBacteria of the species Aerococcus urinae are Gram-positive, catalase-negative cocci that are arranged in pairs, tetrads, or clusters resembling enterococci or staphylococci. They are rare causative agents of infective endocarditis. Repetitive urinary tract infections based upon underlying genitourinary tract abnormalities could involve these bacteria. Due to their similarity to other Gram-positive cocci misinterpretation may occur along the line of microbiologic differentiation, which could potentially lead to a fatal outcome.We herein report on the clinical course of a 68year-old male patient who in the setting of an embolic stroke was initially diagnosed with a culture-negative acute infective endocarditis of the aortic valve.Culture-negative Infective Endocarditis of the Aortic Valve due to Aerococcus urinae: A Rare Aetiology - Corrected ProofAnthony Alozie, Can Yerebakan, Bernd Westphal, Gustav Steinhoff, Andreas Podbielski10.1016/j.hlc.2011.08.005Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010833/abstract?rss=yesDetection of a rapidly growing mass in the right atrium during routine inter-echocardiogram follow-up period in two patients after corrective open-heart surgery raises concerns about nature of the mass and the probable cause. One turned out to be an atrial myxoma that grew rapidly over a eight month period and the other a well encapsulate thrombus in a fully anticoagulated patient. Preoperative transthoracic echocardiogram had reported both the cases to be a myxoma. This article highlights the importance of considering rare causes in the face of a seemingly obvious diagnosis and possible use of imaging modalities in the management of these cases.Right atrial mass after open heart surgery: Tumour or thrombus? - Corrected ProofSuresh Babu Kale, Ashish Badkhal, Natarajan Meenakshinatan Kumar, Jagannathan Raghavan10.1016/j.hlc.2011.08.006Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010869/abstract?rss=yesWe present the case of a 46 year-old male, HCV infected, treated with corrective surgery for tetralogy of Fallot (TOF) immediately after percutaneous closure of the Blalock Taussig shunt. Four months later, the patient had infective endocarditis by Staphylococcus capitis localised on the right side of the patch, treated by oxacillin and gentamycin. The particularity of our report is the unusual location of the acute endocarditis and the bacterium involved: the pulmonary valve is much more likely involved in endocarditis in TOF patients and the patch endocarditis has rarely been reported. Moreover, Staphylococcus capitis has never been reported as a cause of acute endocarditis in corrected TOF patients. We believe that antibiotic therapy should be instituted as soon as possible even though an aggressive surgical treatment is mandatory to achieve complete recovery, mainly when clinical condition and inflammation markers do not improve.Acute endocarditis of the patch caused by Staphylococcus capitis in treated tetralogy of Fallot. An unusual location by an unusual bacterium - Corrected ProofDaniela Demarie, Enrico De Vivo, Enrico Cecchi, Giovanna Marletta, Pier Giuseppe Forsennati, Riccardo Casabona, Fabrizio Sansone, Emanuele Bignamini10.1016/j.hlc.2011.08.009Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611010882/abstract?rss=yesImaging of Left Main Coronary Artery Thrombus with CT Coronary Angiography - Corrected Proof10.1016/j.hlc.2011.08.011Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17http://www.heartlungcirc.org/article/PIIS1443950611010936/abstract?rss=yesWe present the case of right ventricular thrombus formation associated with a right ventricular infarct secondary to a proximal right coronary artery thrombus, which was not evident on transthoracic echocardiography but detected on both delayed gadolinium enhanced magnetic resonance imaging and microsphere contrast echocardiography. The diagnosis of right ventricular thrombosis altered the decision to place an implantable cardiac defibrillator in this patient. Anticoagulation with warfarin resulted in resolution of the thrombus. This case highlights the utility of multimodality imaging in the detection and follow-up of right ventricular thrombus in the setting of right ventricular myocardial infarction, and the effectiveness of anticoagulation therapy.Right Ventricular Thrombus Detection and Multimodality Imaging Using Contrast Echocardiography and Cardiac Magnetic Resonance Imaging - Corrected ProofBenjamin K.-T. Tsang, David G. Platts, George Javorsky, Martin R. Brown10.1016/j.hlc.2011.08.012Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611011607/abstract?rss=yesRomiplostim is a thrombopoietin receptor agonist that increases platelet counts and restores platelet function in patients with chronic immune thrombocytopenia (ITP). Increase in platelet count and platelet activation has been associated with increased thromboembolic risk. The present case report describes an interesting case of acute stent thombosis in a patient with chronic immune thrombocytopenic purpura (ITP) being treated with romiplostim.A Case of Acute Stent Thrombosis During Treatment with the Thrombopoietin Receptor Agonist Peptide—Romiplostim - Corrected ProofRinku Rayoo, Naveen Sharma, William J. van Gaal10.1016/j.hlc.2011.09.001Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHThttp://www.heartlungcirc.org/article/PIIS1443950611011619/abstract?rss=yesChurg–Strauss syndrome (CSS) is a multisystem disorder characterised by asthma, prominent peripheral blood eosinophilia, and vasculitis signs. We report the case of a 22 year-old man admitted to the intensive care unit for acute myocarditis complicated with cardiogenic shock. Eosinophilia, history of asthma, lung infiltrates, paranasal sinusitis, glomerulonephritis, and abdominal pain suggested the diagnosis of CSS. Cardiac MRI confirmed cardiac involvement with a diffuse subendocardial delayed enhancement of the left ventricular wall, and a left ventricular ejection fraction (LVEF) of 30%. Acute myocarditis was confirmed with myocardial biopsy. The patient was successfully treated with systemic corticosteroids, intravenous cyclophosphamide, vasopressor inotropes, intra-aortic balloon pump and mechanical ventilation, and was discharged 21 days later. One year after diagnosis, the patient was asymptomatic. The eosinophilic cell count was normal. Follow-up MRI at one year showed LVEF of 40% with persistent delayed enhancement. Cardiac involvement by CSS requires immediate therapy with corticosteroids and cyclophosphamide, which may allow recovery of the cardiac function.Churg–Strauss Syndrome Presenting with Acute Myocarditis and Cardiogenic Shock - Corrected ProofPierre-Yves Courand, Pierre Croisille, Chahéra Khouatra, Vincent Cottin, Gilbert Kirkorian, Eric Bonnefoy10.1016/j.hlc.2011.09.002Heart, Lung and Circulation (2011)2011-10-17Heart, Lung and Circulation2011-10-17CLINICAL SPOTLIGHT