Background: Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with
normal systolic function, diastolic dysfunction but no symptoms of heart failure (HF).
Our objective was to determine the clinical phenotype and progression to the development
of symptoms in a group of patients with moderate or severe diastolic dysfunction as
determined by Doppler criteria without any symptoms of HF (dyspnoea or oedema or fatigue)
at the time of echocardiography.
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© 2007 Published by Elsevier Inc.
