Heart, Lung and Circulation
Abstract| Volume 17, SUPPLEMENT 1, S9-S10, 2008

Progression of preclinical diastolic dysfunction to the development of symptoms

      Background: Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with normal systolic function, diastolic dysfunction but no symptoms of heart failure (HF). Our objective was to determine the clinical phenotype and progression to the development of symptoms in a group of patients with moderate or severe diastolic dysfunction as determined by Doppler criteria without any symptoms of HF (dyspnoea or oedema or fatigue) at the time of echocardiography.
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