Introduction: Autologous vascular conduits particularly the internal mammary artery remain the
gold standard for coronary artery bypass surgery. However when limited by the availability
or quality of such conduits a suitable synthetic alternative remains lacking. Intensive
research over the last 60 years has seen a myriad of approaches to the development
of a synthetic vascular conduit but methodological limitations have impaired the realisation
of commercial candidates. Despite this, important recent advances in polymer chemistry
and tissue engineering have brought us to the brink of a synthetic vascular conduit
for coronary artery bypass surgery.
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© 2011 Published by Elsevier Inc.
