Heart, Lung and Circulation
Abstract| Volume 20, ISSUE 4, P257, April 2011

Synthetic Vascular Conduits for Coronary Artery Bypass Surgery. Synopsis and State of the Art

      Introduction: Autologous vascular conduits particularly the internal mammary artery remain the gold standard for coronary artery bypass surgery. However when limited by the availability or quality of such conduits a suitable synthetic alternative remains lacking. Intensive research over the last 60 years has seen a myriad of approaches to the development of a synthetic vascular conduit but methodological limitations have impaired the realisation of commercial candidates. Despite this, important recent advances in polymer chemistry and tissue engineering have brought us to the brink of a synthetic vascular conduit for coronary artery bypass surgery.
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