Introduction: A single or dual-dose strategy for myocardial protection is attractive in long operations, in avoiding the need to interrupt the reconstruction to readminister cardioplegia. We hypothesised that a single administration of Bretschneider histidine-tryptophan-ketoglutarate crystalloid solution (Custodiol) offers myocardial protection comparable to repeated antegrade plus retrograde warm blood cardioplegia.
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© 2011 Published by Elsevier Inc.