Introduction: Aspirin is associated with increased bleeding during and after cardiac surgery, but
it may also reduce thrombotic complications. We do not know whether there is a net
benefit or risk from stopping aspirin. Antifibrinolytics such as tranexamic acid can
reduce bleeding after cardiac surgery, but we do not know whether antifibrinolytics
increase the risk of thrombotic complications such as MI or stroke. There are no large
randomised trials to guide our practice [
[1]
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References
- Aprotinin and lysine analogs in high-risk cardiac surgery.N Engl J Med. 2008;
- Aspirin and tranexamic acid for coronary artery surgery (ATACAS) trial: rationale and design.Am Heart J. 2009;
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© 2011 Published by Elsevier Inc.