Introduction: While the current optimal non-emergent revascularisation strategy in patients with
both diabetes mellitus and coronary heart disease is unclear. Prior randomised clinical
trials (RCTs) and meta analyses support coronary artery bypass grafting (CABG) in
patients with multi-vessel disease (MVD) and proximal left anterior descending artery
(LAD) stenosis. RCTs, the largest being the FREEDOM Trial,
1Future REvascularisation Evaluation in patients with Diabetes mellitus: Optimal management
of Multivessel disease.
have randomised these patients to CABG or percutaneous coronary intervention (PCI).
Interpretation and applicability of clinical trial results may be limited if randomised
patients are not typical of those in routine practice. The aim of this study was to
identify potential bias in the choice of revascularisation strategy in patients who
were eligible but not randomised in the FREEDOM Trial at Liverpool Hospital between
June, 2006 and March, 2010.To read this article in full you will need to make a payment
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© 2011 Published by Elsevier Inc.
