Introduction: Malignant pleural mesothelioma (MPM) is known to have an aggressive natural history with a life expectancy of less than 12 months. In recent decades, a number of studies have shown encouraging results for extrapleural pneumonectomy (EPP), especially as part of a multi-modality therapy. However, EPP can be associated with prohibitive morbidity and mortality rates, and appropriate patient selection is vital to ensure optimal surgical outcome. The present systematic review aims to identify the significant prognostic factors for patients who undergo EPP in order to improve the patient selection process.
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© 2011 Published by Elsevier Inc.