Introduction: Malignant pleural mesothelioma (MPM) is known to have an aggressive natural history
with a life expectancy of less than 12 months. In recent decades, a number of studies
have shown encouraging results for extrapleural pneumonectomy (EPP), especially as
part of a multi-modality therapy. However, EPP can be associated with prohibitive
morbidity and mortality rates, and appropriate patient selection is vital to ensure
optimal surgical outcome. The present systematic review aims to identify the significant
prognostic factors for patients who undergo EPP in order to improve the patient selection
process.
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© 2011 Published by Elsevier Inc.
