Clinical Spotlight| Volume 22, ISSUE 4, P303-304, April 2013

Download started.


A Rare Case of Cholesterol Granuloma in the Anterior Mediastinum

Published:August 20, 2012DOI:
      Cholesterol granulomas are reactant lesions that develop in response to cholesterol crystals and foreign body giant cells. They are a commonly described benign condition affecting the middle ear and paranasal sinuses, however have been reported in various sites within the body. We describe a rare case of an incidental cholesterol granuloma in the anterior mediastinum of a cardiac surgical patient.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Heart, Lung and Circulation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Luckraz H.
        • Coulston J.
        • Azzu A.
        Cholesterol granuloma of the superior mediastinum.
        Ann Thorac Surg. 2006; 81: 1509-1510
        • Fujimoto K.
        • Takamori S.
        • Yano H.
        • Sadohara J.
        • Matsuo T.
        • Terazaki Y.
        • et al.
        Focal cholesterol granuloma in the anterior mediastinum: [18F]-fluoro-2-deoxy-d-glucose-positron emission tomography and magnetic resonance imaging findings.
        J Thorac Oncol. 2007; 2: 1054-1056
        • Gore M.
        • Zanation A.
        • Ebert C.
        • Senior B.
        Cholesterol granuloma of the petrous apex.
        Otolaryngol Clin North Am. 2011; 44: 1043-1058
        • Nikolaidis V.
        • Malliari H.
        • Psifidis D.
        • Metaxas S.
        Cholesterol granuloma presenting as a mass obstructing the external ear canal.
        BMC Ear Nose Throat Disord. 2010; 10: 4
        • Leon M.
        • Chavez C.
        • Fyfe B.
        • Nagorsky M.
        • Garcia F.
        Cholesterol granuloma of the maxillary sinus.
        Arch Pathol Lab Med. 2002; 126: 217-219