Advertisement
Heart, Lung and Circulation
Original Article| Volume 23, ISSUE 3, P256-264, March 2014

Favourable Anatomy After End-to-Side Repair of Interrupted Aortic Arch

Published:September 23, 2013DOI:https://doi.org/10.1016/j.hlc.2013.08.006

      Objective

      To evaluate cardiovascular outcomes in patients with aortic arch repair and their possible correlation with arch geometry.

      Methods

      Ten patients who underwent end-to-side repair for aortic arch interruption (IAA), older than 10 years were compared to a cohort of 10 post coarctation (CoA) repair patients matched for age, sex and age at repair. Mean age at operation was 9.7 ± 6.5 days. Patients underwent a resting and 24 h blood pressure measurements, exercise study, MRI, transthoracic echocardiography and vascular studies.

      Results

      Seven patients developed hypertension, two from IAA group and five from CoA group. Nine patients (45%) had gothic arch geometry, three from IAA group and six from CoA group. Despite differences in arch geometry, both groups had normal LV mass, LV function and vascular function.

      Conclusion

      No differences in functional or morphologic outcomes could be demonstrated between the end-to-side repair of the arch by sternotomy and the conventional coarctation repair by thoracotomy. A favourable arch geometry can be achieved after the end-to-side repair of the aortic arch. In the present study, we could not correlate adverse arch geometry with any adverse cardio-vascular outcomes. After neonatal arch repair, the contributive role of aortic arch geometry to late hypertension remains uncertain.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Heart, Lung and Circulation
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Smith Maia M.M.d.C.
        • Cortes T.M.
        • Parga J.R.
        • De Avila L.F.R.
        • Aiello V.D.
        • Barbero-Marcial M.
        • et al.
        Evolutional aspects of children and adolescents with surgically corrected aortic coarctation: clinical, echocardiographic, and magnetic resonance image analysis of 113 patients.
        J Thorac Cardiovasc Surg. 2004; 127 ([see comment]): 712-720
        • O‘Sullivan J.J.
        • Derrick G.
        • Darnell R.
        Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24 hour blood pressure measurement.
        Heart. 2002; 88 ([see comment]): 163-166
        • Cohen M.
        • Fuster V.
        • Steele P.M.
        • Driscoll D.
        • McGoon D.C.
        Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction.
        Circulation. 1989; 80: 840-845
        • Clarkson P.M.
        • Nicholson M.R.
        • Barratt-Boyes B.G.
        • Neutze J.M.
        • Whitlock R.M.
        Results after repair of coarctation of the aorta beyond infancy: a 10 to 28 year follow-up with particular reference to late systemic hypertension.
        Am J Cardiol. 1983; 51: 1481-1488
        • Hoimyr H.
        • Christensen T.D.
        • Emmertsen K.
        • Johnsen S.P.
        • Riis A.
        • Hansen O.K.
        • et al.
        Surgical repair of coarctation of the aorta: up to 40 years of follow-up.
        Eur J Cardiothorac Surg. 2006; 30: 910-916
        • Presbitero P.
        • Demarie D.
        • Villani M.
        • Perinetto E.A.
        • Riva G.
        • Orzan F.
        • et al.
        Long term results (15–30 years) of surgical repair of aortic coarctation.
        Br Heart J. 1987; 57: 462-467
        • Weber H.S.
        • Cyran S.E.
        • Grzeszczak M.
        • Myers J.L.
        • Gleason M.M.
        • Baylen B.G.
        Discrepancies in aortic growth explain aortic arch gradients during exercise.
        J Am Coll Cardiol. 1993; 21: 1002-1007
        • Kappetein A.P.
        • Zwinderman A.H.
        • Bogers A.J.
        • Rohmer J.
        • Huysmans H.A.
        More than thirty-five years of coarctation repair an unexpected high relapse rate.
        J Thorac Cardiovasc Surg. 1994; 107: 87-95
        • Liu J.Y.J.
        • Kowalski R.
        • Jones B.
        • Konstantinov I.E.
        • Cheung M.M.H.
        • Donath S.
        • et al.
        Moderately hypoplastic arches: do they reliably grow into adulthood after conventional coarctation repair?.
        Interact Cardiovasc Thorac Surg. 2010; 10: 582-586
        • Hussein A.
        • Iyengar A.J.
        • Jones B.
        • Donath S.M.
        • Konstantinov I.E.
        • Grigg L.E.
        • et al.
        Twenty-three years of single-stage end-to-side anastomosis repair of interrupted aortic arches.
        J Thorac Cardiovasc Surg. 2010; 139: 942
        • Lee M.G.Y.
        • Kowalski R.
        • Galati J.C.
        • Cheung M.M.H.
        • Jones B.
        • Koleff J.
        • et al.
        Twenty-four-hour ambulatory blood pressure monitoring detects a high prevalence of hypertension late after coarctation repair in patients with hypoplastic arches.
        J Thorac Cardiovasc Surg. 2012; 144: 1110-1118
        • Rakhra S.S.
        • Lee M.
        • Iyengar A.J.
        • Wheaton G.R.
        • Grigg L.
        • Konstantinov I.E.
        • et al.
        Poor outcomes after surgery for coarctation repair with hypoplastic arch warrants more extensive initial surgery and close long-term follow-up.
        Interact Cardiovasc Thorac Surg. 2012; 11: 11
        • Ou P.
        • Bonnet D.
        • Auriacombe L.
        • Pedroni E.
        • Balleux F.
        • Sidi D.
        • et al.
        Late systemic hypertension and aortic arch geometry after successful repair of coarctation of the aorta.
        Eur Heart J. 2004; 25 ([see comment]): 1853-1859
        • Colan S.D.
        • Parness I.A.
        • Spevak P.J.
        • Sanders S.P.
        Developmental modulation of myocardial mechanics: age- and growth-related alterations in afterload and contractility.
        J Am Coll Cardiol. 1992; 19: 619-629
        • Abbott R.D.
        • Gutgesell H.P.
        Effects of heteroscedasticity and skewness on prediction in regression: modeling growth of the human heart.
        Methods Enzymol. 1994; 240: 37-51
        • Altman D.G.
        Construction of age-related reference centiles using absolute residuals.
        Stat Med. 1993; 12: 917-924
        • Ellestad M.H.
        Stress testing: principles and practice.
        2nd ed. F.A. Davis Co., Philadelphia1980
        • Manolio T.A.
        • Burke G.L.
        • Savage P.J.
        • Sidney S.
        • Gardin J.M.
        • Oberman A.
        Exercise blood pressure response and 5-year risk of elevated blood pressure in a cohort of young adults: the CARDIA study.
        Am J Hypertens. 1994; 7: 234-241
        • Cumming G.R.
        • Everatt D.
        • Hastman L.
        Bruce treadmill test in children: normal values in a clinic population.
        Am J Cardiol. 1978; 41: 69-75
        • Eidem B.W.
        • McMahon C.J.
        • Cohen R.R.
        • Wu J.
        • Finkelshteyn I.
        • Kovalchin J.P.
        • et al.
        Impact of cardiac growth on Doppler tissue imaging velocities: a study in healthy children.
        J Am Soc Echocardiogr. 2004; 17: 212-221
        • Denarié N.
        • Simon A.
        • Chironi G.
        • Gariepy J.
        • Kumlin L.
        • Massonneau M.
        • et al.
        Difference in carotid artery wall structure between Swedish and French men at low and high coronary risk.
        Stroke. 2001; 32: 1775-1779
        • Denarié N.
        • Gariepy J.
        • Chironi G.
        • Massonneau M.
        • Laskri F.
        • Salomon J.
        • et al.
        Distribution of ultrasonographically-assessed dimensions of common carotid arteries in healthy adults of both sexes.
        Atherosclerosis. 2000; 148: 297-302
        • Juonala M.
        • Kahonen M.
        • Laitinen T.
        • Hutri-Kahonen N.
        • Jokinen E.
        • Taittonen L.
        • et al.
        Effect of age and sex on carotid intima-media thickness, elasticity and brachial endothelial function in healthy adults: the cardiovascular risk in Young Finns Study.
        Eur Heart J. 2008; 29: 1198-1206
        • Ou P.
        • Mousseaux E.
        • Celermajer D.S.
        • Pedroni E.
        • Vouhe P.
        • Sidi D.
        • et al.
        Aortic arch shape deformation after coarctation surgery: effect on blood pressure response.
        J Thorac Cardiovasc Surg. 2006; 132: 1105-1111
        • Ou P.
        • Celermajer D.S.
        • Raisky O.
        • Jolivet O.
        • Buyens F.
        • Herment A.
        • et al.
        Angular (Gothic) aortic arch leads to enhanced systolic wave reflection, central aortic stiffness, and increased left ventricular mass late after aortic coarctation repair: evaluation with magnetic resonance flow mapping.
        J Thorac Cardiovasc Surg. 2008; 135: 62-68
        • Urbina E.
        • Alpert B.
        • Flynn J.
        • Hayman L.
        • Harshfield G.A.
        • Jacobson M.
        • et al.
        Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young and the Council for High Blood Pressure Research.
        Hypertension. 2008; 52: 433-451
        • Pickering T.G.
        • Hall J.E.
        • Appel L.J.
        • Falkner B.E.
        • Graves J.
        • Hill M.N.
        • et al.
        Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research.
        Hypertension. 2005; 45 ([see comment]): 142-161
        • Ou P.
        • Celermajer D.S.
        • Mousseaux E.
        • Giron A.
        • Aggoun Y.
        • Szezepanski I.
        • et al.
        Vascular remodeling after “successful” repair of coarctation: impact of aortic arch geometry.
        J Am Coll Cardiol. 2007; 49: 883-890
        • Aminbakhsh A.
        • Mancini G.B.
        • Aminbakhsh A.
        • Mancini G.B.
        Carotid intima-media thickness measurements: what defines an abnormality? A systematic review.
        Clin Invest Med. 1999; 22 ([see comment]): 149-157
        • Kadono T.
        • Sugiyama H.
        • Hoshiai M.
        • Osada M.
        • Tan T.
        • Naitoh A.
        • et al.
        Endothelial function evaluated by flow-mediated dilatation in pediatric vascular disease.
        Pediatr Cardiol. 2005; 26: 385-390
        • Thijssen D.H.
        • van Bemmel M.M.
        • Bullens L.M.
        • Dawson E.A.
        • Hopkins N.D.
        • Tinken T.M.
        • et al.
        The impact of baseline diameter on flow-mediated dilation differs in young and older humans.
        Am J Physiol Heart Circ Physiol. 2008; 295: H1594-H1598
        • De Caro E.
        • Trocchio G.
        • Smeraldi A.
        • Calevo M.G.
        • Pongiglione G.
        Aortic arch geometry and exercise-induced hypertension in aortic coarctation.
        Am J Cardiol. 2007; 99: 1284-1287
        • Lashley D.
        • Curtin J.
        • Malcolm P.
        • Clark A.
        • Freeman L.
        Aortic arch morphology and late systemic hypertension following correction of coarctation of aorta.
        Congenit Heart Dis. 2007; 2: 410-415
        • Vriend J.W.J.
        • Oosterhof T.
        • Hazekamp M.G.
        • Mulder B.J.M.
        Aortic arch morphology and hypertension in post-coarctectomy patients.
        Eur Heart J. 2005; 26 ([see comment]): 941