Randomised control trials (RCT) are considered the gold standard for the strength
of evidence used in formulation of guidelines in the contemporary clinical practice.
The analysis is based on the design of an experiment that analyses data collected
in a future event space with no regard to past observations. It bases its conclusions
on arbitrary values of significance that might not be clinically relevant or plausible.
A Bayesian analysis looks at all the past evidence and observations to reach a conclusion
and does not have the shortcomings of a RCT.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Heart, Lung and CirculationAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The History of Statistics: The Measurement of Uncertainty before 1900.Harvard University Press, Cambridge, MA1990
- An Essay towards solving a Problem in the Doctrine of Chances.Philosophical Transactions of the Royal Society of London. 1763; 53: 370-418
- Bayesian methods in health technology assessment: a review.Health Technol Assess. 2000; 4: 1-130
- Priors for the design and analysis of clinical trials.in: Berry D.A. Stangl D.K. Bayesian biostatistics. Marcel Dekker, New York1996: 157-184
- Two internal thoracic artery grafts are better than one.J Thorac Cardiovasc Surg. 1999; 117: 855-872
- A meta-analysis comparing bilateral internal mammary artery with left internal mammary artery for coronary artery bypass grafting.Ann Cardiothorac Surg. 2013; 2: 390-400
- The right internal thoracic artery: the forgotten conduit--5,766 patients and 991 angiograms.Ann Thorac Surg. 2011; 92: 9-15
Article info
Publication history
Published online: December 11, 2014
Accepted:
December 2,
2014
Received:
October 11,
2014
Identification
Copyright
© 2015 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier Inc. All rights reserved.
