Background
Prognostic impact of anaemia in the elderly with acute coronary syndromes has not
been specifically analysed, and little information exists about causes of mortality
in this setting.
Methods
We prospectively included consecutive patients with acute coronary syndromes. Anaemia
was defined as haemoglobin < 130 g/L in men, and < 120 g/L in women. Primary outcome was mid-term mortality and its causes. Analyses were
performed by Cox regression method.
Results
We included 2128 patients, of whom 394 (18.6%) were aged 75 years or older. Anaemia
was more common in the elderly (40.4% vs 19.5%, p <0.001). Mean follow-up was 386
days. Anaemia independently predicted overall mortality (HR 1.47, 95% CI 1.05-2.06),
cardiac mortality (HR 1.76, 95% CI 1.06-2.94) and non-cardiac mortality (HR 1.59,
95% CI 1.03-2.45) in the overall cohort. In young patients the association between
anaemia and mortality was significant only for non-cardiac causes. The association
between anaemia and mortality was not significant in the elderly (HR 1.08, 95% CI
0.71-1.63, p 0.736).
Conclusions
The impact of anaemia on cause specific of mortality seem to be different according
to age subgroup. The association between anaemia and mortality was not observed in
elderly patients from our series.
Keywords
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Article info
Publication history
Published online: December 23, 2014
Accepted:
December 3,
2014
Received in revised form:
November 29,
2014
Received:
October 6,
2014
Identification
Copyright
© 2014 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier Inc. All rights reserved.
