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Heart, Lung and Circulation
Clinical Spotlight| Volume 24, ISSUE 8, e130-e132, August 2015

Effective Treatment of Intermediate-Risk Pulmonary Embolism by Manual Thrombus Aspiration. A Report of Two Cases

Published:April 29, 2015DOI:https://doi.org/10.1016/j.hlc.2015.03.024
      Manual thrombectomy, part of the armamentarium of interventional cardiologists, might also be considered as an effective and safe alternative to manage intermediate/high risk acute PE patients with contraindications to thrombolysis or with acute haemodynamic decompensation. We here describe two cases with intermediate risk pulmonary embolism and severe hypoxaemia where manual thrombectomy with a 10F dedicated catheter was effective and improved clinical and haemodynamic parameters. Currently, there's no clear and effective treatment for these patients, thus we believe that this therapy, as current ESC guidelines suggest, should become a possible alternative to systemic thrombolysis and anticoagulant regimen.

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      References

        • Konstantinides S.
        • Torbicki A.
        • Agnelli G.
        • Danchin N.
        • Fitzmaurice D.
        • Galiè N.
        • et al.
        2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: European Society of Cardiology (ESC) Endorsed by the European Respiratory Society (ERS).
        European Heart Journal. 2014; 35: 3033-3073
        • Meyer G.
        • Vicaut E.
        • Konstantinides S.V.
        Fibrinolysis for intermediate-risk pulmonary embolism.
        N Engl J Med. 2014; 371: 581-582
        • Kuo W.T.
        • Gould M.K.
        • Louie J.D.
        • Rosenberg J.K.
        • Sze D.Y.
        • Hofmann L.V.
        Catheter-directed therapy for the treatment of massive pulmonary embolism: systematic review and meta-analysis of modern techniques.
        J Vasc Interv Radiol. 2009; 20: 1431-1440
        • Stein P.D.
        • Athanasoulis C.
        • Alavi A.
        • Greenspan R.H.
        • Hales C.A.
        • Saltzman H.A.
        • et al.
        Complications and validity of pulmonary angiography in acute pulmonary embolism.
        Circulation. 1992; 85: 462-468
        • Braude S.
        • Martens-Nielsen J.
        Severe refractory hypoxaemia in submassive pulmonary embolism: a surrogate marker of severe right ventricular dysfunction and indication for thrombolysis.
        Intern Med J. 2012; 42: 712-715
        • Bayiz H.
        • Dumantepe M.
        • Teymen B.
        • Uyar I.
        Percutaneous Aspiration Thrombectomy in Treatment of Massive Pulmonary Embolism.
        Heart, Lung and Circulation. 2015; 24: 46-54