Atrial fibrillation (AF) and left ventricular systolic dysfunction (LVSD) are two cardiovascular conditions that are increasing in incidence worldwide [
]. Both conditions are associated with worsened survival and morbidity, in addition to significant economic burdens upon health care systems [
- Chugh S.S.
- Havmoeller R.
- Narayanan K.
- Singh D.
- Rienstra M.
- Benjamin E.J.
- et al.
Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study.
Circulation. 2014; 129: 837-847
]. Shared pathophysiological mechanisms mean that each condition can perpetuate the other, often making the temporal relationship between the two difficult to determine [
- Cook C.
- Cole G.
- Asaria P.
- Jabbour R.
- Francis D.P.
The annual global economic burden of heart failure.
International Journal of Cardiology. 2014; 171: 368-376
]. Nonetheless, such a distinction may be critical, particularly where AF is driving the LVSD, as treatment of the AF may potentially improve or even reverse the LVSD.
- Prabhu S.
- Voskoboinik A.
- Kaye D.M.
- Kistler P.M.
Atrial Fibrillation and Heart Failure; Cause or Effect?.
Heart, Lung and Circulation. 2017;
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- Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study.Circulation. 2014; 129: 837-847
- The annual global economic burden of heart failure.International Journal of Cardiology. 2014; 171: 368-376
- Atrial Fibrillation and Heart Failure; Cause or Effect?.Heart, Lung and Circulation. 2017;
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© 2018 Published by Elsevier Inc.