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Editorial| Volume 31, ISSUE 3, P301-303, March 2022

Time to Reconsider the Diagnosis of “Left Ventricular Noncompaction” in Adults?

  • Samantha Barratt Ross
    Affiliations
    Agnes Ginges Centre for Molecular Cardiology Centenary Institute, The University of Sydney, Sydney, NSW, Australia

    Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia

    Wiser Healthcare, The University of Sydney, Sydney, NSW, Australia
    Search for articles by this author
  • Alexandra Barratt
    Affiliations
    Wiser Healthcare, The University of Sydney, Sydney, NSW, Australia

    Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia
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  • Christopher Semsarian
    Correspondence
    Corresponding author at: Centenary Institute, Locked Bag 6, Newtown, NSW, 2042 Australia.
    Affiliations
    Agnes Ginges Centre for Molecular Cardiology Centenary Institute, The University of Sydney, Sydney, NSW, Australia

    Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia

    Wiser Healthcare, The University of Sydney, Sydney, NSW, Australia

    Department of Cardiology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Search for articles by this author
Published:November 24, 2021DOI:https://doi.org/10.1016/j.hlc.2021.10.016
Time to Reconsider the Diagnosis of “Left Ventricular Noncompaction” in Adults?
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      Left ventricular non-compaction (LVNC) is characterised by a bi-layered myocardium, with excessive left ventricular (LV) trabeculation. Ongoing debate exists as to whether LVNC in adults is a distinct cardiomyopathy, or a morphological feature of ventricular remodelling present in physiological and pathological states. In this commentary, we explore how an increase in the diagnosis amongst the healthy adult population, in addition to cardiovascular cohorts and athletes [
      • Ross S.B.
      • Jones K.
      • Blanch B.
      • Puranik R.
      • McGeechan K.
      • Barratt A.
      • et al.
      A systematic review and meta-analysis of the prevalence of left ventricular non-compaction in adults.
      Eur Heart J. 2020; 41: 1428-1436
      ], has led to likely overdiagnosis or misdiagnosis—whereby a diagnosis leads to more harm than benefit. We propose a clinically meaningful diagnostic pathway to reduce these potential harms.

      Keywords

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      References

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        A systematic review and meta-analysis of the prevalence of left ventricular non-compaction in adults.
        Eur Heart J. 2020; 41: 1428-1436
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      Article info

      Publication history

      Published online: November 24, 2021
      Accepted: October 29, 2021
      Received in revised form: October 29, 2021
      Received: October 15, 2021

      Identification

      DOI: https://doi.org/10.1016/j.hlc.2021.10.016

      Copyright

      © 2021 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

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