Background
ABO blood groups are considered to be associated with cardiovascular disease. Nonetheless,
the definite effect of ABO blood groups on the clinical outcome of coronary artery
bypass graft surgery (CABG) is still undetermined. We evaluated whether ABO blood
groups can predict long-term major adverse cardiocerebrovascular events (MACCE) in
CABG patients.
Method
In this retrospective cohort study, we retrieved the clinical files of eligible patients
treated with isolated CABG in our hospital between March 2007 and March 2016. We divided
the patients into four ABO subgroups. The primary study endpoints were the occurrence
of all-cause mortality and MACCE during long-term follow-ups. We used Cox regression
survival analysis to define the association of ABO blood groups with the occurrence
of MACCE.
Results
Of 17,892 patients who underwent isolated CABG, 17,713 (mean age, 61.19±9.47 years,
74.6% male) were successfully followed, and their data used in the final analysis.
Our multivariable analysis demonstrated that patients with different blood groups
had similar 5-year mortality and 5-year MACCE.
Conclusions
Our findings suggest that in patients who underwent CABG, ABO blood groups were not
associated with long-term MACCE.
Keywords
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Article info
Publication history
Published online: January 21, 2022
Accepted:
November 12,
2021
Received in revised form:
October 12,
2021
Received:
August 9,
2020
Identification
Copyright
© 2021 Published by Elsevier B.V. on behalf of Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ).
