Background
Little is known about the impact of a coarctation repair on the functional outcomes
of young adults. This study aimed to determine (1) the functional and mental health
status in young adults with previous coarctation repair, and (2) the impact of late
hypertension on their quality of life.
Methods
A cross-sectional study using validated self-reported questionnaires (Short Form 36
version 2 [SF-36v2], Beck Depression Inventory [BDI], and State-Trait Anxiety Inventory
[STAI]) was performed in 54 patients aged 15–47 years with previous paediatric coarctation
repair. Questionnaire scores were compared to healthy age- and gender-matched controls.
Patients’ previously published 24-hour blood pressure monitoring results were included.
Results
Late hypertension was present in 64% (34/54) at a mean of 29±8 years after coarctation
repair. SF-36v2 mean physical component summary score was significantly lower in coarctation
patients compared with controls (53.1±6.8 vs 56.0±4.7, p=0.02), but there was no significant
difference in mean mental component summary score (p=0.2). SF-36v2 mean role emotional
score tended to be associated with 10 mmHg increases in mean 24-hour systolic blood
pressure (regression coefficient 4.3 p=0.06). STAI mean trait anxiety score tended
to be higher in coarctation patients compared with controls (36.6±9.0 vs 33.5±7.8,
p=0.06). There was no significant difference in BDI scores between patients and controls.
Conclusions
Young adults with previous coarctation repair report poorer physical health and tended
towards higher anxiety trait compared to healthy controls. Strategies to improve self-reported
physical health and anxiety should be explored. Long-term assessment of quality of
life outcomes in coarctation patients is warranted.
Keywords
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Article info
Publication history
Published online: January 19, 2022
Accepted:
December 1,
2021
Received in revised form:
March 13,
2021
Received:
July 13,
2020
Identification
Copyright
© 2021 Published by Elsevier B.V. on behalf of Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ).
