Advertisement
Heart, Lung and Circulation
Original Article|Articles in Press

Declining Public Awareness of Heart Attack Warning Symptoms in the Years Following an Australian Public Awareness Campaign: A Cross-Sectional Study

Open AccessPublished:February 16, 2023DOI:https://doi.org/10.1016/j.hlc.2023.01.010

      Background

      The National Heart Foundation of Australia’s (NHFA) Warning Signs campaign ran between 2010 and 2013. This study examines trends in Australian adults’ ability to name heart attack symptoms during the campaign and in the years following.

      Methods

      Using the NHFA’s HeartWatch data (quarterly online surveys) for adults aged 30–59 years, we conducted an adjusted piecewise regression analysis comparing trends in the ability to name symptoms during the campaign period plus one year lag (2010–2014) to the post-campaign period (2015–2020)

      Results

      Over the study period, there were 101,936 Australian adults surveyed. Symptom awareness was high or increased during the campaign period. However, there was a significant downward trend in each year following the campaign period for most symptoms (e.g., chest pain: adjusted odds ratio [AOR] =0.91, 95%CI: 0.56–0.80; arm pain: AOR=0.92, 95%CI: 0.90–0.94). Conversely, the inability to name any heart attack symptom increased in each year following the campaign (3.7% in 2010 to 19.9% in 2020; AOR=1.13, 95%CI: 1.10–1.15); these respondents were more likely to be younger, male, have less than 12 years of education, identify as Aboriginal and/or Torres Strait Islander Peoples, speak a language other than English at home and have no cardiovascular risk factors.

      Conclusion

      Awareness of heart attack symptoms has decreased in the years since the Warning Signs campaign in Australia, with 1 in 5 adults currently unable to name a single heart attack symptom. New approaches are needed to promote and sustain this knowledge, and to ensure people act appropriately and promptly if symptoms occur.

      Keywords

      Mass media health campaigns are widely used to expose large proportions of populations to messages about health and to promote behaviour change. There is now a large body of evidence demonstrating that these campaigns can be an effective means of changing population-based knowledge and beliefs, but a more varied response appears to be seen with behaviour change [
      • Wakefield M.A.
      • Loken B.
      • Hornik R.C.
      Use of mass media campaigns to change health behaviour.
      ]. Common elements of successful campaigns include sufficient funding to provide frequent exposure over time, adequate access to promoted services, knowing how to reach the target audience, appropriate and sensitive messaging, and addressing known barriers to behaviour change [
      • Wakefield M.A.
      • Loken B.
      • Hornik R.C.
      Use of mass media campaigns to change health behaviour.
      ].
      In the 2000s international evidence showed that many patients experiencing heart attack symptoms were not eligible for time-sensitive critical treatments as they were presenting to hospital too late, or were dying at home [
      • Moser D.K.
      • Kimble L.P.
      • Alberts M.J.
      • Alonzo A.
      • Croft J.B.
      • Dracup K.
      • et al.
      Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on cardiovascular nursing and stroke council.
      ,
      • Finn J.C.
      • Bett J.H.
      • Shilton T.R.
      • Cunningham C.
      • Thompson P.L.
      National Heart Foundation of Australia Chest Pain Every Minute Counts Working G. Patient delay in responding to symptoms of possible heart attack: can we reduce time to care?.
      ]. Major barriers included not recognising symptoms as heart-related or as serious, not wanting to cause a fuss or trouble others, and seeking medical attention from their local doctor [
      • Moser D.K.
      • Kimble L.P.
      • Alberts M.J.
      • Alonzo A.
      • Croft J.B.
      • Dracup K.
      • et al.
      Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on cardiovascular nursing and stroke council.
      ]. Following a review of international literature, the National Heart Foundation of Australia (NHFA) recognised the need to educate the Australian public about heart attack symptoms and the appropriate behaviour to act fast and call an ambulance (i.e., emergency medical services [EMS]). In 2009, the NHFA employed an advertising agency to develop and pilot the Warning Signs campaign, which then ran across Australian mass media between 2010 and 2013. This AUD$16 million national strategy included mass media education on typical, less common and associated symptoms of acute coronary syndrome (ACS). The campaign also addressed the known barriers to prehospital delay and calling EMS [
      • Moser D.K.
      • Kimble L.P.
      • Alberts M.J.
      • Alonzo A.
      • Croft J.B.
      • Dracup K.
      • et al.
      Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on cardiovascular nursing and stroke council.
      ] and specifically targeted middle-aged adults.
      While active, the campaign had excellent reach [
      • Bray J.E.
      • Stub D.
      • Ngu P.
      • Cartledge S.
      • Straney L.
      • Stewart M.
      • et al.
      Mass media campaigns' influence on prehospital behavior for acute coronary syndromes: an evaluation of the Australian Heart Foundation's Warning Signs campaign.
      ] and was associated with improvements in ACS treatment-seeking behaviour [
      • Bray J.E.
      • Stub D.
      • Ngu P.
      • Cartledge S.
      • Straney L.
      • Stewart M.
      • et al.
      Mass media campaigns' influence on prehospital behavior for acute coronary syndromes: an evaluation of the Australian Heart Foundation's Warning Signs campaign.
      ,
      • Eastwood K.
      • Howell S.
      • Nehme Z.
      • Finn J.
      • Smith K.
      • Cameron P.
      • et al.
      Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome.
      ] and a reduction in the incidence of out-of-hospital cardiac arrest [
      • Nehme Z.
      • Andrew E.
      • Bernard S.
      • Patsamanis H.
      • Cameron P.
      • Bray J.E.
      • et al.
      Impact of a public awareness campaign on out-of-hospital cardiac arrest incidence and mortality rates.
      ]. However, these evaluations also suggested a waning effect following the campaign, and the long-term impacts of this campaign on symptom awareness have not been reported. A recent review [
      • Hoschar S.
      • Albarqouni L.
      • Ladwig K.H.
      A systematic review of educational interventions aiming to reduce prehospital delay in patients with acute coronary syndrome.
      ] reported no studies that examined the long-term impacts of similar international heart attack campaigns beyond three years, and subgroups (e.g., those with known risk factors) were rarely examined.
      Over the campaign period and in the years following the campaign to September 2020, the NHFA tracked the awareness of ACS symptoms in middle-aged Australian adults (aged 30–59 years) through online quarterly surveys, known as the HeartWatch Data. The aim of this study was to examine the long-term impact of the Warning Signs campaign on the awareness of ACS symptoms in Australian adults. We also aimed to examine the impact on predetermined sub-groups, such as those with cardiovascular risk factors (e.g., history of heart disease or hypertension). Such information is vital to informing policy and practice regarding public education.

      Methods

      We conducted a retrospective cross-sectional study of the HeartWatch survey data, which was prospectively collected quarterly on Australian adults, aged 30 to 59 years, between 2010 and 2020. This study was approved by the Monash University Ethics Committee (2020-26102-48329).

      The Warning Signs Campaign

      The Warning Signs campaign was a multi-media campaign that ran between 2010 and 2013 across Australian television, radio, digital and print (newspapers and magazines) media and in movie cinemas. The campaign was piloted in three regions (Melbourne, Geelong and Broken Hill) in late 2009, and then ran intermittently across the country between February 2010 and September 2011 and for all of 2013. A funded national campaign on non-subscription television channels and radio occurred between October 2011 and December 2012, and this was active for one month in every 2–3 months. The symptoms described varied across the types of media used, with the major television campaign describing chest tightness, jaw pain and shortness of breath. All media (television advertisements and radio announcements, billboards, and newspaper advertisements) included a web address to learn the warning signs. The main feature of the campaign were two television advertisements targeted at Australian adults aged over 45 years. The first advert showed a deceased white male describing his heart attack symptoms and the actions he should have taken (e.g., calling an ambulance) and the second advertisement showed a cardiologist addressing the known barriers to reacting early to symptoms (e.g., downplaying or denying symptoms) and calling an ambulance (e.g., embarrassment).

      Participants and Survey

      Respondents were Australian adults participating in market research surveys. The surveys were conducted online every four months by three independent market research companies. Selection of survey respondents was based on age, sex and regions (state/territory) quotas to reflect the demographics and locations of the Australian population. The companies used non-probability online panels recruited through opt-in methods with small funding compensation (AUD$2 to AUD$3).
      For this study, we chose to examine the subgroup of adults aged between 30 and 59 years, as this age group included the target audience of the Warning Signs campaign and were surveyed in every quarter of the study period.

      Data Collection and Variables

      We obtained de-identified HeartWatch data for the study period. Data collected included demographics, self-reported cardiovascular medical history and risk factors, and unprompted awareness of heart attack warning signs (Supplementary materials). The market research company categorised responses to the open-ended symptom question into symptoms (based on NHFA input) or a “none” category if no symptoms were given.
      Table 1Demographics and self-reported risk factors of those surveyed overall and comparison by campaign period.
      DemographicsOverall

      N (%)
      Campaign Period + 1 Year Lag 2010–2014

      N (%)
      Post-Campaign Period

      2015–2020

      N (%)
      P-value
      Age groups<0.001
       30–3415,347 (15.1)7,726 (14.3)7,621 (15.9)
       35–3915,393 (15.1)7,898 (14.6)7,495 (15.6)
       40–4416,762 (16.4)9,270 (17.1)7,492 (15.6)
       45–4917,405 (17.1)9,446 (17.5)7,959 (16.6)
       50–5417,664 (17.3)9,583 (17.7)8,081 (16.9)
       55–5919,365 (19.0)10,128 (18.7)9,237 (19.3)
      Sex<0.001
       Female53,959 (52.9)27,984 (51.8)25,975 (54.2)
       Male47,977 (47.1)26,067 (48.2)21,910 (45.8)
      Region<0.001
       New South Wales17,447 (17.1)8,492 (15.7)8,955 (18.7)
       Victoria17,300 (17.0)8,540 (15.8)8,760 (18.3)
       Queensland15,640 (15.3)8,391 (15.5)7,249 (15.1)
       South Australia12,792 (12.5)6,949 (12.9)5,843 (12.2)
       Western Australia13,839 (13.6)7,117 (13.2)6,722 (14.0)
       Northern Territory7,315 (7.2)4,176 (7.7)3,139 (6.6)
       Tasmania9,073 (8.9)5,323 (9.8)3,750 (7.8)
       Australian Capital Territory8,530 (8.4)5,063 (9.4)3,467 (7.2)
      Aboriginal and/or Torres Strait Islander<0.001
       Yes2,095 (2.1)790 (1.5)1,305 (2.7)
       No99,841 (97.9)53,261 (98.5)46,580 (97.3)
      Language other than English at home<0.001
       Yes15,327 (15.0)6,854 (12.7)8,473 (17.7)
       No86,609 (85.0)47,197 (87.3)39,412 (82.3)
      Highest level of education<0.001
       <12 years31,579 (31.0)18,940 (35.0)12,639 (26.4)
       Vocational/TAFE35,517 (34.8)19,318 (35.7)16,199 (33.8)
       University34,840 (34.2)15,793 (29.2)19,047 (39.8)
      Self-reported cardiovascular risk factors
       Hypertension33,208 (32.6)19,176 (35.5)14,032 (29.3)<0.001
       Hypercholesteraemia33,724 (33.1)19,577 (36.3)14,147 (29.5)<0.001
       Diabetes9,852 (9.7)5,473 (10.1)4,379 (9.1)<0.001
       Heart disease5,055 (5.0)2,855 (5.3)2,200 (4.6)<0.001
      Bold highlighted cells represent cells where the observed count is significantly higher than the expected count.
      Abbreviation: TAFE, Technical and Further Education.

      Statistical Analysis

      Baseline characteristics are summarised as counts and percentages with stratification by campaign period. Differences in baseline characteristics across the two periods were assessed using Pearson’s chi-squared test. Pearson’s standardised residuals were used to identify table cells where the observed counts were significantly higher than would be expected under the null hypothesis of independence. While this does not provide direct head-to-head comparisons between the proportions of two (or more) cells, it has been offered as a proxy post hoc test [
      • Sharpe D.
      Chi-Square test is statistically significant: Now what?.
      ]. A standardised residual greater than 2 is determined to be significant.
      Trends over the study period were assessed for the main symptoms of interest (chest pain, arm pain) and the inability to name a symptom using piecewise logistic regression models [
      • Ryan S.
      • Porth L.
      • Porth S.
      A Tutorial on the piecewise regression approach applied to bedload transport data.
      ]. This is a form of regression that allows separate linear models to be fitted to the data for different ranges of x (the independent variable) in a single model. Knots (or breakpoints) are the values of x where the slope of the linear function changes and separate regression lines are estimated for data on each side of the knot. In our study, yearly quarter represents the independent (x) variable and a knot was set a priori at the first quarter of 2015. This provides separate regression lines for the campaign period plus a one-year lag (Jan 2010–Dec 2014) and for the post-campaign period (Jan 2015–Sep 2020). A one-year lag period was selected based on previous short-term evaluations of the Warning Signs campaign which reported the presence of a short-term lag effect [
      • Nehme Z.
      • Andrew E.
      • Bernard S.
      • Patsamanis H.
      • Cameron P.
      • Bray J.E.
      • et al.
      Impact of a public awareness campaign on out-of-hospital cardiac arrest incidence and mortality rates.
      ,
      • Nehme Z.
      • Cameron P.A.
      • Akram M.
      • Patsamanis H.
      • Bray J.E.
      • Meredith I.T.
      • et al.
      Effect of a mass media campaign on ambulance use for chest pain.
      ]. Cluster-robust estimates of standard errors were applied to account for clustering of observations within state. All models were adjusted for responder’s demographics captured in the HeartWatch data (age, sex, level of education, primary language spoken, Aboriginal and/or Torres Strait Islander) and the presence of any self-reported cardiovascular risk factors.
      Stratified analyses were undertaken to identify subgroups of interest amongst males and females, Aboriginal and/or Torres Strait Islanders and non-Indigenous responders, English and non-English primary language speakers, as well as amongst respondents who reported heart disease, hypertension, diabetes and hypercholesteraemia. The results are expressed as annual trends across the campaign and post-campaign periods and the immediate annual change comparing 2015 to 2014.
      While the data was collected at quarterly intervals and analysed using yearly quarter as the independent variable, results across the campaign and post-campaign periods are reported as annual trends. Annual trends were calculated by multiplying the regression model coefficients by a constant and then exponentiating the result to provide an odds ratio.
      All tests were two-tailed and assessed at the 5% alpha level. Adjustment for multiple testing was not undertaken as disjunction null hypothesis tests, which require such adjustments, were not undertaken [
      • Rubin M.
      When to adjust alpha during multiple testing: a consideration of disjunction, conjunction, and individual testing.
      ].

      Results

      Over the study period (January 2010 to September 2020), there were 101,936 Australian adults aged between 30 and 59 years surveyed: 53% were female, 34% had a university qualification, 15% spoke a language other than English at home, 53% reported having a cardiovascular risk factor, and 2.1% were Aboriginal or Torres Strait Islanders (Table 1). There were significant differences across campaign periods on all demographic characteristics and self-reported risk factors (Table 1).
      As is seen in Figure 1A and Table 2, respondents’ awareness of chest and arm pain as symptoms of a heart attack was relatively high and stable during the campaign period and for the one-year lag period. However, after adjusting for differences in the sample over time, respondents’ awareness of both chest pain and arm pain decreased significantly in both the first year (compared to the lag year, all p<0.001) and every year following the campaign (chest pain adjusted odds ratio [AOR] =0.91, 95%CI: 0.56–0.80, p<0.001; and arm pain AOR=0.92, 95%CI: 0.90–0.94, p<0.001), compared to the campaign period. Awareness of other types of pain (jaw, back, shoulder and neck pain) and some associated symptoms (shortness of breath and sweating) as heart attack symptoms were seen to increase during the campaign, but followed a similar downward trend after the campaign (Figures 1B and 1C).
      Figure thumbnail gr1
      Figure 1Annual trends in the proportion of Australian adult HeartWatch respondents’ ability to name (A) typical or no symptoms, (B) other regions of pain and (C) associated heart attack symptoms (shaded years are periods when the campaign was active, dark green is the paid national campaign).
      Table 2Impact of the Warning Signs campaign on Australian adults’ awareness of chest pain, arm pain and inability to name any heart attack symptom (don’t know).
      Chest painArm painDon’t know
      OR95% CIPOR95% CIPOR95% CIP
      Campaign activity (annual trend)
       Campaign0.970.95, 1.010.111.000.98, 1.030.711.091.00, 1.190.05
       Post-campaign0.910.89, 0.92<0.0010.920.90, 0.94<0.0011.131.10, 1.15<0.001
       Immediate change (2015 v 2014)0.670.56, 0.80<0.0010.760.69, 0.84<0.0011.741.06, 2.830.03
      Age (years)
       30–340.550.49, 0.61<0.0010.550.51, 0.59<0.0012.312.01, 2.66<0.001
       35–390.650.61, 0.70<0.0010.660.60, 0.72<0.0011.881.65, 2.13<0.001
       40–440.730.68, 0.77<0.0010.730.69, 0.77<0.0011.631.42, 1.88<0.001
       45–490.800.74, 0.87<0.0010.850.80, 0.89<0.0011.391.22, 1.60<0.001
       50–540.900.83, 0.970.010.910.84, 0.990.031.251.11, 1.41<0.001
       55–591.001.001.00
      Sex
       Male1.001.001.00
       Female1.421.34, 1.51<0.0012.061.95, 2.18<0.0010.540.50, 0.58<0.001
      Education
       Year 12 or less1.001.001.00
       TAFE/Vocational/Diploma1.211.15, 1.27<0.0011.211.17, 1.25<0.0010.720.67, 0.77<0.001
       University1.261.16, 1.38<0.0011.281.20, 1.37<0.0010.630.55, 0.72<0.001
      Aboriginal and Torres Strait Islander
       No1.001.001.00
       Yes0.690.52, 0.910.0080.810.68, 0.950.011.781.30, 2.42<0.001
      Language other than English
       No1.001.001.00
       Yes0.560.52, 0.59<0.0010.540.51, 0.58<0.0011.751.64, 1.87<0.001
      Any cardiovascular risk factor
       No1.001.001.00
       Yes1.061.01, 1.110.0081.111.06, 1.16<0.0010.870.80, 0.94<0.001
      Abbreviations: OR, odds ratio; CI, confidence intervals; TAFE, Technical and Further Education.
      Conversely, as seen in Figure 2, the proportion of respondents unable to name a single heart symptom increased in the period following the campaign (3.7% in 2010 to 19.9% in 2020), after adjusting for demographics there was an increase in each year following the campaign of 13% (AOR=1.13, 95%CI: 1.10–1.15, p<0.001) (Table 2 and Figure 1A). Respondents who were unable to name a single symptom were more likely to be male, younger than 55 years, have less than or 12 years of education, identify as Aboriginal and/or Torres Strait Islanders, speak a language other than English at home and report no cardiovascular risk factors. Statistical models in subgroups showed similar adjusted trends (Table 3).
      Figure thumbnail gr2
      Figure 2An unadjusted subgroup comparison of the proportion of respondents unable to name a single heart attack symptom in the years 2010 and 2020 (all p<0.001).
      Table 3Impact of the Warning Signs campaign for awareness of chest pain, arm pain and inability to name any heart attack symptom (don’t know) for the stratified analysis in specific groups.
      Chest painArm painDon’t know
      OR95% CIPOR95% CIPOR95% CIP
      Self-reported heart disease
       Campaign activity (annual trend)
       Campaign0.990.92, 1.060.790.990.95, 1.030.591.040.93, 1.180.48
       Post-campaign0.940.87, 1.010.080.930.90, 0.97<0.0011.091.01, 1.170.03
       Immediate change (2015 v 2014)0.490.36, 0.67<0.0010.710.58, 0.880.0012.741.64, 4.56<0.001
      Self-reported hypertension
       Campaign activity (annual trend)
       Campaign0.970.94, 1.010.141.010.98, 1.040.621.091.02, 1.160.01
       Post-campaign0.900.88, 0.91<0.0010.940.91, 0.96<0.0011.141.11, 1.17<0.001
       Immediate change (2015 v 2014)0.700.59, 0.85<0.0010.730.64, 0.83<0.0011.751.14, 2.710.01
      Self-reported diabetes
       Campaign activity (annual trend)
       Campaign1.000.95, 1.040.921.010.97, 1.050.741.081.00, 1.160.04
       Post-campaign0.890.86, 0.92<0.0010.910.87, 0.94<0.0011.151.11, 1.20<0.001
       Immediate change (2015 v 2014)0.640.49, 0.830.0010.770.68, 0.88<0.0011.651.11, 2.460.01
      Self-reported hypercholesteraemia
      Campaign activity (annual trend)
       Campaign1.010.97, 1.040.711.020.99, 1.060.241.050.96, 1.150.26
       Post-campaign0.930.91, 0.95<0.0010.950.92, 0.97<0.0011.121.09, 1.17<0.001
       Immediate change (2015 v 2014)0.620.52, 0.75<0.0010.720.61, 0.85<0.0011.881.21, 2.930.005
      Males
       Campaign activity (annual trend)
       Campaign0.980.94, 1.020.261.010.97, 1.060.541.050.98, 1.130.16
       Post-campaign0.900.89, 0.91<0.0010.910.88, 0.93<0.0011.131.10, 1.15<0.001
       Immediate change (2015 v 2014)0.630.52, 0.78<0.0010.770.66, 0.890.0011.821.22, 2.710.003
      Females
       Campaign activity (annual trend)
       Campaign0.970.95, 1.000.031.000.98, 1.010.701.151.00, 1.320.05
       Post-campaign0.910.89, 0.94<0.0010.930.91, 0.95<0.0011.121.08, 1.17<0.001
       Immediate change (2015 v 2014)0.710.62, 0.83<0.0010.760.70, 0.82<0.0011.610.84, 3.110.15
      Aboriginal and Torres Strait Islander Peoples
       Campaign activity (annual trend)
       Campaign0.950.86, 1.050.311.010.85, 1.200.891.281.06, 1.540.009
       Post-campaign0.850.79, 0.93<0.0010.850.77, 0.930.0011.201.09, 1.33<0.001
       Immediate change (2015 v 2014)0.840.64, 1.120.240.710.45, 1.120.140.870.44, 1.750.70
      Non-Indigenous
       Campaign activity (annual trend)
       Campaign0.980.95, 1.010.121.000.98, 1.030.701.080.99, 1.190.07
       Post-campaign0.910.89, 0.93<0.0010.920.91, 0.94<0.0011.121.10, 1.15<0.001
       Immediate change (2015 v 2014)0.670.56, 0.79<0.0010.760.69, 0.84<0.0011.771.09, 2.880.02
      Language other than English at home
       Campaign activity (annual trend)
       Campaign1.000.96, 1.040.940.940.92, 0.97<0.0011.040.98, 1.110.20
       Post-campaign0.920.90, 0.95<0.0010.920.90, 0.95<0.0011.081.04, 1.13<0.001
       Immediate change (2015 v 2014)0.580.50, 0.69<0.0010.810.72, 0.90<0.0011.851.39, 2.47<0.001
      Speaks English only at home
       Campaign activity (annual trend)
       Campaign0.970.94, 1.000.051.010.99, 1.040.351.101.00, 1.210.05
       Post-campaign0.900.89, 0.92<0.0010.920.90, 0.94<0.0011.141.11, 1.16<0.001
       Immediate change (2015 v 2014)0.690.58, 0.83<0.0010.760.68, 0.84<0.0011.710.98, 2.970.06
      Abbreviations: OR, odds ratio; CI, confidence intervals; TAFE, Technical and Further Education.

      Discussion

      Our study suggests the awareness of ACS symptoms in middle-aged Australian adults was greatest during the years the Warnings Signs campaign was active, but has steadily decreased in the following seven years. Of particular concern, by 2020 only 50% of respondents reported chest pain as a heart attack symptom and one in five adults could not name a single symptom. These results were consistent across most demographic subgroups and in respondents with self-reported cardiovascular risk factors.
      While baseline data were not available, the results suggest no increase was seen in the awareness of the more common symptoms of ACS (i.e., chest and arm pain) across the campaign period. This may have occurred because those who saw or heard the campaign materials were already aware of these symptoms as they are commonly used to portray heart attack symptoms in the media. Studies in Australian ACS patients cite television as a common source of heart attack information [
      • Dracup K.
      • Hassenplug L.W.
      • McKinley S.M.
      • Moser D.K.
      Australian patients' delay in response to heart attack symptoms.
      ], and a survey conducted in the Australian state of Victoria in the early 2000s showed similar rates of chest pain (84.5%) and arm pain (56.1%) to those reported in our study [
      • Smith K.L.
      • Cameron P.A.
      • Meyer A.
      • McNeil J.J.
      Knowledge of heart attack symptoms in a community survey of Victoria.
      ]. International surveys have also reported high awareness of chest pain (68% to 90%) but more variable awareness of arm pain (14% to 70%) and other symptoms in the general public [
      • Barnhart J.M.
      • Cohen O.
      • Kramer H.M.
      • Wilkins C.M.
      • Wylie-Rosett J.
      Awareness of heart attack symptoms and lifesaving actions among New York City area residents.
      ,
      • Luan S.
      • Yang Y.
      • Huang Y.
      • McDowell M.
      Public knowledge of stroke and heart attack symptoms in China: a cross-sectional survey.
      ,
      • Goff Jr., D.C.
      • Sellers D.E.
      • McGovern P.G.
      • Meischke H.
      • Goldberg R.J.
      • Bittner V.
      • et al.
      Knowledge of heart attack symptoms in a population survey in the United States: The REACT Trial.
      ,
      • Mata J.
      • Frank R.
      • Gigerenzer G.
      Symptom recognition of heart attack and stroke in nine European countries: a representative survey.
      ]. Importantly, one study reported 68% of ACS patients who were aware of the Warning Signs campaign stated it increased their awareness of symptoms [
      • Bray J.E.
      • Stub D.
      • Ngu P.
      • Cartledge S.
      • Straney L.
      • Stewart M.
      • et al.
      Mass media campaigns' influence on prehospital behavior for acute coronary syndromes: an evaluation of the Australian Heart Foundation's Warning Signs campaign.
      ], and a prominent effect of the campaign in our findings was an increase in the lesser-known regions of pain (e.g., jaw, shoulder, neck and back) which was one of the aims of the campaign.
      A recent systematic review reported that the few international studies that examined the impact of mass media campaigns on the public’s symptom knowledge were mostly conducted in small, localised samples [
      • Hoschar S.
      • Albarqouni L.
      • Ladwig K.H.
      A systematic review of educational interventions aiming to reduce prehospital delay in patients with acute coronary syndrome.
      ]. A strength of our study is the large and national sample. The highest quality study, the Rapid Early Action for Coronary Treatment (REACT) trial [
      • Luepker R.V.
      • Raczynski J.M.
      • Osganian S.
      • Goldberg R.J.
      • Finnegan Jr., J.R.
      • Hedges J.R.
      • et al.
      Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: The Rapid Early Action for Coronary Treatment (REACT) Trial.
      ] in the USA, used a randomised controlled design to examine public symptom knowledge following an 18-month public and patient education campaign in pair-matched communities. These authors reported intervention communities had only a modest increase in their knowledge of the number of heart attack symptoms, compared to control communities, and that this effect appeared to take approximately 12 months to be realised [
      • Goff Jr., D.C.
      • Mitchell P.
      • Finnegan J.
      • Pandey D.
      • Bittner V.
      • Feldman H.
      • et al.
      Knowledge of heart attack symptoms in 20 US communities. Results from the Rapid Early Action for Coronary Treatment Community Trial.
      ]. However, awareness of chest pain was high in both the intervention and control groups at baseline, and there was no real effect for any other specific symptom [
      • Goff Jr., D.C.
      • Mitchell P.
      • Finnegan J.
      • Pandey D.
      • Bittner V.
      • Feldman H.
      • et al.
      Knowledge of heart attack symptoms in 20 US communities. Results from the Rapid Early Action for Coronary Treatment Community Trial.
      ].
      Our findings of a significant impact on symptom knowledge during the campaign are in alignment with other evaluations of the Warning Signs campaign. These, population-based studies conducted in Victoria, report an increase in EMS use in ACS and chest pain patients [
      • Nehme Z.
      • Cameron P.A.
      • Akram M.
      • Patsamanis H.
      • Bray J.E.
      • Meredith I.T.
      • et al.
      Effect of a mass media campaign on ambulance use for chest pain.
      ,
      • Eastwood K.
      • Howell S.
      • Nehme Z.
      • Finn J.
      • Smith K.
      • Cameron P.
      • et al.
      Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome.
      ], and a decrease in out-of-hospital cardiac arrest incidence [
      • Nehme Z.
      • Andrew E.
      • Bernard S.
      • Patsamanis H.
      • Cameron P.
      • Bray J.E.
      • et al.
      Impact of a public awareness campaign on out-of-hospital cardiac arrest incidence and mortality rates.
      ]. Evaluations in other regions of Australia, which also report high awareness of the campaign, showed no effect of the campaign on EMS use in patients with suspected ACS or on time to presentation in ACS patients [
      • Tummala S.R.
      • Farshid A.
      Patients' understanding of their heart attack and the impact of exposure to a media campaign on pre-hospital time.
      ,
      • Lavery T.
      • Greenslade J.H.
      • Parsonage W.A.
      • Hawkins T.
      • Dalton E.
      • Hammett C.
      • et al.
      Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study.
      ,
      • Coventry L.L.
      • Bremner A.P.
      • van Schalkwyk J.W.
      • Hegney D.G.
      • Thompson P.L.
      The effect of media campaigns, patient characteristics, and presenting symptoms on prehospital delay in myocardial infarction patients: a prospective cohort study.
      ]. However, these three studies were conducted in single centres using convenience samples and were likely to be underpowered to detect any effect.
      Our study is the first we are aware of examining the long-term effects following a mass media heart attack warning signs campaign. Our data suggest any knowledge gains from large-scale mass media campaigns are only seen for the following year. Studies of campaigns for other conditions, such as stroke, have found continuous impacts with short-term annual mass media campaigns [
      • Bray J.E.
      • Finn J.
      • Cameron P.
      • Smith K.
      • Straney L.
      • Cartledge S.
      • et al.
      Temporal trends in emergency medical services and general practitioner use for acute stroke after Australian public education campaigns.
      ,
      • Bray J.E.
      • Johnson R.
      • Trobbiani K.
      • Mosley I.
      • Lalor E.
      • Cadilhac D.
      • et al.
      Australian public's awareness of stroke warning signs improves after national multimedia campaigns.
      ], suggesting the need for ongoing public awareness messages. However, such campaigns are expensive and need to compete with other health messaging. Lessons learnt from the REACT trial suggest a better use of funds and resources may be direct messaging to those who are at the highest risk and in whom the message has not yet penetrated [
      • Luepker R.V.
      • Raczynski J.M.
      • Osganian S.
      • Goldberg R.J.
      • Finnegan Jr., J.R.
      • Hedges J.R.
      • et al.
      Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: The Rapid Early Action for Coronary Treatment (REACT) Trial.
      ].
      Similar to our findings, the previous Victorian and international surveys have also reported lower symptom awareness in subgroups of the public including men [
      • Smith K.L.
      • Cameron P.A.
      • Meyer A.
      • McNeil J.J.
      Knowledge of heart attack symptoms in a community survey of Victoria.
      ,
      • Ratner P.A.
      • Johnson J.L.
      • Mackay M.
      • Tu A.W.
      • Hossain S.
      Knowledge of “heart attack” symptoms in a Canadian urban community.
      ], those with lower levels of education [
      • Smith K.L.
      • Cameron P.A.
      • Meyer A.
      • McNeil J.J.
      Knowledge of heart attack symptoms in a community survey of Victoria.
      ] or no history of heart disease [
      • Smith K.L.
      • Cameron P.A.
      • Meyer A.
      • McNeil J.J.
      Knowledge of heart attack symptoms in a community survey of Victoria.
      ,
      • Goff Jr., D.C.
      • Sellers D.E.
      • McGovern P.G.
      • Meischke H.
      • Goldberg R.J.
      • Bittner V.
      • et al.
      Knowledge of heart attack symptoms in a population survey in the United States: The REACT Trial.
      ], and in culturally and linguistically diverse populations [
      • Smith K.L.
      • Cameron P.A.
      • Meyer A.
      • McNeil J.J.
      Knowledge of heart attack symptoms in a community survey of Victoria.
      ,
      • Goff Jr., D.C.
      • Sellers D.E.
      • McGovern P.G.
      • Meischke H.
      • Goldberg R.J.
      • Bittner V.
      • et al.
      Knowledge of heart attack symptoms in a population survey in the United States: The REACT Trial.
      ,
      • Ratner P.A.
      • Johnson J.L.
      • Mackay M.
      • Tu A.W.
      • Hossain S.
      Knowledge of “heart attack” symptoms in a Canadian urban community.
      ]. Our study also identified lower awareness of symptoms in Aboriginal and/or Torres Strait Islanders who are harder to reach with health messaging and in whom co-design of interventions is recommended [
      • Nash S.
      • Arora A.
      Interventions to improve health literacy among Aboriginal and Torres Strait Islander Peoples: a systematic review.
      ]. The declining awareness of heart attack symptoms seen across all subgroups, including those who are at higher risk with cardiovascular risk factors, since the Warning Signs campaign is alarming. New methods are needed to improve overall knowledge, reach hard-to-reach groups, and sustain knowledge gains. Such interventions could also consider targeting regions with high rates of ACS which can be identified in some regions of Australia through the Heart Foundation’s Heart Maps. [
      National Heart Foundation of Australia
      Heart Maps.
      ].

      Limitations

      As the NHFA is the main cardiovascular body in Australia, we are confident no other national heart attack campaigns have occurred since the Warnings Signs campaign. However, these results should be interpreted with caution considering the limitations of online surveys (e.g., responder bias and fraud), even with quota sampling to reflect some of the demographics of the underlying population, and the lack of pre-campaign data. The quota and online sampling methods used may mean that some sections of the population are under-represented. The generalisability of the findings to the wider Australian adult population may therefore be limited and requires further research.

      Conclusion

      Our data suggest large mass media campaigns are effective at educating the public on both typical and less common ACS signs and symptoms, but this effect is not maintained once exposure to advertising ceases. Mass media campaigns either need to be continued, or new approaches are needed, to ensure prompt recognition and response to signs and symptoms.

      Acknowledgements

      We wish to thank the Heart Foundation Staff who assisted with the provision of data and campaign details.

      Sources of Funding

      JB (#104751), ZN (#105690), DS (#105793), SC (#104860) are funded by the National Heart Foundation, of Australia Fellowships. JF is funded by a National Health and Medical Research Council, Australia Investigator Grant (#1174838).

      Disclosures

      Investigators are funded (JB, ZN, DS, JF) or employed (AB) by the Heart Foundation of Australia. The funding body was not involved in the analysis or reporting of the data. SH conducted the statistical analysis.

      Appendices

      References

        • Wakefield M.A.
        • Loken B.
        • Hornik R.C.
        Use of mass media campaigns to change health behaviour.
        Lancet. 2010; 376: 1261-1271
        • Moser D.K.
        • Kimble L.P.
        • Alberts M.J.
        • Alonzo A.
        • Croft J.B.
        • Dracup K.
        • et al.
        Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on cardiovascular nursing and stroke council.
        Circulation. 2006; 114: 168-182
        • Finn J.C.
        • Bett J.H.
        • Shilton T.R.
        • Cunningham C.
        • Thompson P.L.
        National Heart Foundation of Australia Chest Pain Every Minute Counts Working G. Patient delay in responding to symptoms of possible heart attack: can we reduce time to care?.
        Med J Aust. 2007; 187: 293-298
        • Bray J.E.
        • Stub D.
        • Ngu P.
        • Cartledge S.
        • Straney L.
        • Stewart M.
        • et al.
        Mass media campaigns' influence on prehospital behavior for acute coronary syndromes: an evaluation of the Australian Heart Foundation's Warning Signs campaign.
        J Am Heart Assoc. 2015; 4
        • Eastwood K.
        • Howell S.
        • Nehme Z.
        • Finn J.
        • Smith K.
        • Cameron P.
        • et al.
        Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome.
        Open Heart. 2021; 8
        • Nehme Z.
        • Andrew E.
        • Bernard S.
        • Patsamanis H.
        • Cameron P.
        • Bray J.E.
        • et al.
        Impact of a public awareness campaign on out-of-hospital cardiac arrest incidence and mortality rates.
        Eur Heart J. 2017; 38: 1666-1673
        • Hoschar S.
        • Albarqouni L.
        • Ladwig K.H.
        A systematic review of educational interventions aiming to reduce prehospital delay in patients with acute coronary syndrome.
        Open Heart. 2020; 7e001175
        • Sharpe D.
        Chi-Square test is statistically significant: Now what?.
        PARE. 2015; 20: 1-10
        • Ryan S.
        • Porth L.
        • Porth S.
        A Tutorial on the piecewise regression approach applied to bedload transport data.
        USDA Forest Service General Technical Report RMRS-GTR, 2007
        • Nehme Z.
        • Cameron P.A.
        • Akram M.
        • Patsamanis H.
        • Bray J.E.
        • Meredith I.T.
        • et al.
        Effect of a mass media campaign on ambulance use for chest pain.
        Med J Aust. 2017; 206: 30-35
        • Rubin M.
        When to adjust alpha during multiple testing: a consideration of disjunction, conjunction, and individual testing.
        Synthese. 2021; 199: 10969-11000
        • Dracup K.
        • Hassenplug L.W.
        • McKinley S.M.
        • Moser D.K.
        Australian patients' delay in response to heart attack symptoms.
        Med J Aust. 1997; 166: 233-236
        • Smith K.L.
        • Cameron P.A.
        • Meyer A.
        • McNeil J.J.
        Knowledge of heart attack symptoms in a community survey of Victoria.
        Emerg Med (Fremantle). 2002; 14: 255-260
        • Barnhart J.M.
        • Cohen O.
        • Kramer H.M.
        • Wilkins C.M.
        • Wylie-Rosett J.
        Awareness of heart attack symptoms and lifesaving actions among New York City area residents.
        J Urban Health. 2005; 82: 207-215
        • Luan S.
        • Yang Y.
        • Huang Y.
        • McDowell M.
        Public knowledge of stroke and heart attack symptoms in China: a cross-sectional survey.
        BMJ Open. 2021; 11e043220
        • Goff Jr., D.C.
        • Sellers D.E.
        • McGovern P.G.
        • Meischke H.
        • Goldberg R.J.
        • Bittner V.
        • et al.
        Knowledge of heart attack symptoms in a population survey in the United States: The REACT Trial.
        Arch Intern Med. 1998; 158: 2329-2338
        • Mata J.
        • Frank R.
        • Gigerenzer G.
        Symptom recognition of heart attack and stroke in nine European countries: a representative survey.
        Health Expect. 2014; 17: 376-387
        • Luepker R.V.
        • Raczynski J.M.
        • Osganian S.
        • Goldberg R.J.
        • Finnegan Jr., J.R.
        • Hedges J.R.
        • et al.
        Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: The Rapid Early Action for Coronary Treatment (REACT) Trial.
        JAMA. 2000; 284: 60-67
        • Goff Jr., D.C.
        • Mitchell P.
        • Finnegan J.
        • Pandey D.
        • Bittner V.
        • Feldman H.
        • et al.
        Knowledge of heart attack symptoms in 20 US communities. Results from the Rapid Early Action for Coronary Treatment Community Trial.
        Prev Med. 2004; 38: 85-93
        • Eastwood K.
        • Howell S.
        • Nehme Z.
        • Finn J.
        • Smith K.
        • Cameron P.
        • et al.
        Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome.
        Open Heart. 2021; 8e001792
        • Tummala S.R.
        • Farshid A.
        Patients' understanding of their heart attack and the impact of exposure to a media campaign on pre-hospital time.
        Heart, Lung and Circulation. 2015; 24: 4-10
        • Lavery T.
        • Greenslade J.H.
        • Parsonage W.A.
        • Hawkins T.
        • Dalton E.
        • Hammett C.
        • et al.
        Factors influencing choice of pre-hospital transportation of patients with potential acute coronary syndrome: an observational study.
        Emerg Med Australas. 2017; 29: 210-216
        • Coventry L.L.
        • Bremner A.P.
        • van Schalkwyk J.W.
        • Hegney D.G.
        • Thompson P.L.
        The effect of media campaigns, patient characteristics, and presenting symptoms on prehospital delay in myocardial infarction patients: a prospective cohort study.
        Heart Lung Circ. 2019; 28: 1161-1175
        • Bray J.E.
        • Finn J.
        • Cameron P.
        • Smith K.
        • Straney L.
        • Cartledge S.
        • et al.
        Temporal trends in emergency medical services and general practitioner use for acute stroke after Australian public education campaigns.
        Stroke. 2018; 49: 3078-3080
        • Bray J.E.
        • Johnson R.
        • Trobbiani K.
        • Mosley I.
        • Lalor E.
        • Cadilhac D.
        • et al.
        Australian public's awareness of stroke warning signs improves after national multimedia campaigns.
        Stroke. 2013; 44: 3540-3543
        • Ratner P.A.
        • Johnson J.L.
        • Mackay M.
        • Tu A.W.
        • Hossain S.
        Knowledge of “heart attack” symptoms in a Canadian urban community.
        Clin Med Cardiol. 2008; 2 (CMC.S709.)
        • Nash S.
        • Arora A.
        Interventions to improve health literacy among Aboriginal and Torres Strait Islander Peoples: a systematic review.
        BMC Public Health. 2021; 21: 248
        • National Heart Foundation of Australia
        Heart Maps.
        2022